Zac Efron has trials, tribulations and good looks 

Seth Rogen has a man crush on his “Neighbors” co-star, Zac Efron.

“He’s the sexiest motherf----- alive,” Rogen told host Conan O’Brien on a visit to his show this week.

The “Knocked Up” star reflected on working with Efron, 26, while shooting their comedy earlier this year — and Rogen, 31, said he was often distracted by the “High School Musical” star’s chiseled physique.

Meanwhile, others are more concerned about mounting troubles for the former Disney star, including a suspicious scuffle on Los Angeles’ skid row in March, and possible relapse into drug and alcohol abuse.

Adam Shankman, Efron’s director in “Hairspray,” has offered to be his sober coach, reports. Meanwhile, insiders tell In Touch that the actor, after two reported stints in rehab, is struggling.

Four months ago, drugs led to Zac’s broken jaw, the magazine reports, even though the actor said he slipped in a puddle at his Hollywood Hills home. But the In Touch source says Efron hurt himself during a drug binge: “He even does drugs alone. It’s sad.”

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