Officers responded to reports of a vehicle accident at Third Street and Gilman Avenue about 1 p.m., according to police Sgt. Danielle Newman.
The victim was taken to San Francisco General Hospital to be treated for multiple injuries, police said.
An investigation of the incident is underway, Newman said.
Anyone with information about the incident is encouraged to contact police homicide investigators at (415) 553-1145 or through the anonymous tip line at (415) 575-4444.